IPA-3 (Standard)
IPA-3 (Standard) is the analytical standard of IPA-3. This product is intended for research and analytical applications. IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, and shows no inhibition to group II PAKs (PAKs 4-6).
For research use only. We do not sell to patients.
- CAS No.: 42521-82-4
- Formula: C20H14O2S2
- Molecular Weight:350.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 42521-82-4
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Molecular Weight 350.45
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Formula C20H14O2S2
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SMILES
OC1=CC=C2C=CC=CC2=C1SSC3=C4C=CC=CC4=CC=C3O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Viaud J, et al. An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently. Mol Cancer Ther. 2009 Sep;8(9):2559-65. [Content Brief]
[2]. Flaiz C, et al. PAK kinase regulates Rac GTPase and is a potential target in human schwannomas. Exp Neurol. 2009 Jul;218(1):137-44. [Content Brief]
[3]. Deacon SW, et al. An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. Chem Biol. 2008 Apr;15(4):322-31 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)