AZD1092
AZD1092 is an orally active glucokinase (GK) activator with an EC50 value of 0.03 μM. AZD1092 can be used for the research of Type 2 Diabetes (T2D).
For research use only. We do not sell to patients.
- CAS No.: 871656-65-4
- Formula: C24H26N4O5
- Molecular Weight:450.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
EC50: 0.03 μM (glucokinase)[1]
AZD1092 has activity for glucokinase with an EC50 value of 0.03 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female Zucker rats[1]
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Dosage:1, 3, 10 mg/kg
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Administration:Oral
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Result:Exhibited dose dependent reduction of glucose excursion in oral glucose tolerance tests in high fat fed female Zucker rats and glucose lowering efficacy in free feeding glucose profiles in male Zucker rats.
Chemical Information
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CAS No. 871656-65-4
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Molecular Weight 450.49
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Formula C24H26N4O5
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SMILES
O=C(C1=CC(O[C@H](CO)C)=CC(OC2=CC=C(C=C2)C(N3CCC3)=O)=C1)NC4=NN(C=C4)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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