Benzoquinonium dibromide
Benzoquinonium dibromide is a nicotinic acetylcholine receptors (nAChRs) antagonist, with an IC50 of 0.46 μM. Benzoquinonium dibromide can block neuromuscular and ganglionic transmission.
For research use only. We do not sell to patients.
- Formula: C34H50Br2N4O2
- Molecular Weight:706.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
IC50: 0.46 μM (nAChRs)[1]
Chemical Information
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Molecular Weight 706.59
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Formula C34H50Br2N4O2
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SMILES
O=C(C(NCCC[N+](CC)(CC)CC1=CC=CC=C1)=C2)C=C(NCCC[N+](CC)(CC)CC3=CC=CC=C3)C2=O.[Br-].[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. Walker RJ, et, al. Physiological and pharmacological studies on annelid and nematode body wall muscle. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1993 Sep;106(1):49-58. [Content Brief]
[2]. BOWMAN WC. The neuromuscular blocking action of benzoquinonium chloride in the cat and in the hen. Br J Pharmacol Chemother. 1958 Dec;13(4):521-30. [Content Brief]
[3]. Bowman WC, et, al. Neuromuscular blocking and ganglion blocking activities of some acetylcholine antagonists in the cat. J Pharm Pharmacol. 1972 Oct;24(10):762-72. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Benzoquinonium dibromide Related Classifications
HY-B1552B Related Classifications
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