2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. BG48

BG48 is a potent HDAC inhibitor. BG48 inhibits the enzymatic activity of HDAC1 and HDAC2.

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BG48

BG48 화학구조

CAS No. : 1628784-53-1

사이즈 가격 재고 수량
5 mg 해외재고보유
10 mg 해외재고보유
50 mg   견적 받기  
100 mg   견적 받기  

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BG48 Related Antibodies

Top Publications Citing Use of Products

View All HDAC Isoform Specific Products:

View All Isoforms
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

BG48 is a potent HDAC inhibitor. BG48 inhibits the enzymatic activity of HDAC1 and HDAC2[1].

IC50 & Target[1]

HDAC1

 

HDAC2

 

분자량

441.55

화학식

C25H23N5OS
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=C(C1=CC=C(C=C1)/N=N/C2=CC=C(N(C)C)C=C2)NC3=C(N)C=CC(C4=CC=CS4)=C3
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 100 mg/mL (226.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2647 mL 11.3237 mL 22.6475 mL
5 mM 0.4529 mL 2.2647 mL 4.5295 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2647 mL 11.3237 mL 22.6475 mL 56.6187 mL
5 mM 0.4529 mL 2.2647 mL 4.5295 mL 11.3237 mL
10 mM 0.2265 mL 1.1324 mL 2.2647 mL 5.6619 mL
15 mM 0.1510 mL 0.7549 mL 1.5098 mL 3.7746 mL
20 mM 0.1132 mL 0.5662 mL 1.1324 mL 2.8309 mL
25 mM 0.0906 mL 0.4529 mL 0.9059 mL 2.2647 mL
30 mM 0.0755 mL 0.3775 mL 0.7549 mL 1.8873 mL
40 mM 0.0566 mL 0.2831 mL 0.5662 mL 1.4155 mL
50 mM 0.0453 mL 0.2265 mL 0.4529 mL 1.1324 mL
60 mM 0.0377 mL 0.1887 mL 0.3775 mL 0.9436 mL
80 mM 0.0283 mL 0.1415 mL 0.2831 mL 0.7077 mL
100 mM 0.0226 mL 0.1132 mL 0.2265 mL 0.5662 mL
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BG48 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BG481628784-53-1BG 48BG-48HDACHistone deacetylasesMCF-7 cellsChemo-Optical Modulation of Epigenetically-regulated Transcription’ (COMET)Inhibitorinhibitorinhibit

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Inquiry Information

상품명:
BG48
Cat. No.:
HY-124337
수량:
MCE Japan Authorized Agent:

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비고

SAFETY DATA SHEET (SDS)

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