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Gel filtration chromatography, also known as size-exclusion chromatography or molecular sieve chromatography, achieves separation and purification based on the varying elution rates of molecules of different sizes within the column.
The dextran gel has good stability, commonly used in desalting or buffer exchange. In general, gels with higher degree of cross-linking and smaller pores are suitable for separating bioproducts of low molecular weight, while gels with lower degree of cross-linking and larger pores are suitable forseparating bioproducts of high molecular weight.
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Filter Medium (31)
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CM Cellulose CM-32 (Carboxymethyl cellulose) is a cellulose derivative. CM Cellulose CM-32 has a wide range of applications in the biomedical field, including tissue engineering, wound dressing, absorbent nonwovens, fabrication of 3D-scaffolds for biocompatible implants, artificial organs or mimics of extracellular polymeric matrix and diagnosis of various diseases. CM Cellulose CM-32 can decrease osteoclasts formation. CM Cellulose CM-32 can be used as a biological material or organic compound for life science related research.
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Cross-linked dextran G 200 is a hydrophilic gel based on molecular size exclusion and targeted macromolecular separation. Cross-linked dextran G 200 works through the gel permeation mechanism, and the cross-linked structure forms a three-dimensional network with a specific pore size, achieving separation based on the molecular hydrodynamic volume. Cross-linked dextran G 200 can be used to adjust the osmotic solute distribution coefficient and the ability to maintain osmotic equilibrium, such as in gel filtration chromatography for purification and analysis of biomacromolecules such as proteins and nucleic acids. Cross-linked dextran G 200 can also be used as a gel filtration filler (particle size range: 40-120 μm; globular protein separation range: 5-600 kDa).
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DEAE-Cellulose (Diethylaminoethyl cellulose) is a positively charged weakly basic cellulose anion exchanger. DEAE-Cellulose exhibits gold recovery activity as well as heparin binding/release activity. DEAE-Cellulose can also be used for the purification of proteins, enzymes and nucleic acids.
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Cross-linked dextran G 50 is a gel filtration medium. Cross-linked dextran G 50 can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da).
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Cross-linked dextran G 150 is a hydrophilic gel based on molecular size exclusion and targeted for the separation of macromolecules. Cross-linked dextran G 150 functions through the gel permeation mechanism, where the cross-linked structure forms a three-dimensional network with specific pore diameters, achieving separation based on the molecular volumetric flow. Cross-linked dextran G 150 can be used to regulate the distribution coefficient of permeating solutes and maintain the permeation balance, such as in gel filtration chromatography for the purification and analysis of biological macromolecules like proteins and nucleic acids. Cross-linked dextran G 150 can also be used as a gel filtration filler (particle size range: 40-120 μm; spherical protein separation range: 5-300 kDa).
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- Molecular Weight: 70000 (Average)
Blue dextran (Dextran blue) (MW 70000) is a high-molecular-weight dextran dye and colloidal marker. Blue dextran (MW 70000) exhibits molecular sieve exclusion effects, affinity binding capacity, and biocompatibility and stability. Blue dextran (MW 70000) can be used in research such as human serum protein purification.
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- Molecular Weight: 70000 (Average)
Poly (sodium 4-styrenesulfonate) (MW 70000) is an anionic polyelectrolyte. Poly (sodium 4-styrenesulfonate) (MW 70000) is used as a biochemical reagent.
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Cross-linked dextran G 25, fine is a cross-linked dextran gel chromatography fine (average particle size D50 = 70-90 μm) that possesses multiple separation activities, including molecular sieve effects, weak anion exchange, and aromatic adsorption. Cross-linked dextran G 25, fine weakly exchanges cations through immobilized terminal carboxyl groups and repels anions at low ionic strength. Cross-linked dextran G 25, fine is used for the fractionation of low molecular weight solutes, including peptides, amino acids, nucleotide sugar derivatives, and aromatic compounds.
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Cross-linked dextran G 100 is a gel filtration medium that can be used for protein purification (Sphere protein separation range: 4K-150K Da; Polysaccharide separation range: 1K-100K Da).
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- Molecular Weight: 5000 (Average)
Blue dextran (MW 5000) (Dextran blue (MW 5000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin.
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Cross-linked dextran G 75 is a Gel-filtration media. Cross-linked dextran G 75 also is a dextran-based matrix and used for Gel-filtration chromatography (Particle size range: 40-120 μm; Sphere protein separation range: 3K-80K Da; Polysaccharide separation range: 1K-50K Da).
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- Molecular Weight: 20000 (Average)
Blue dextran (MW 20000) (Dextran blue (MW 20000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin.
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Cross-linked dextran G 25, coarse is a cross-linked dextran gel chromatography coarse (average particle size D50 = 200-250 μm) that possesses multiple separation activities, including molecular sieve effects, weak anion exchange, and aromatic adsorption. Cross-linked dextran G 25, coarse weakly exchanges cations through immobilized terminal carboxyl groups and repels anions at low ionic strength. Cross-linked dextran G 25, coarse is used for the fractionation of low molecular weight solutes, including peptides, amino acids, nucleotide sugar derivatives, and aromatic compounds.
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Cross-linked dextran G 25, medium is a cross-linked dextran gel chromatography medium (average particle size D50 = 120-140 μm) that possesses multiple separation activities, including molecular sieve effects, weak anion exchange, and aromatic adsorption. Cross-linked dextran G 25, medium weakly exchanges cations through immobilized terminal carboxyl groups and repels anions at low ionic strength. Cross-linked dextran G 25, medium is used for the fractionation of low molecular weight solutes, including peptides, amino acids, nucleotide sugar derivatives, and aromatic compounds.
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- Molecular Weight: 500000 (Average)
Blue dextran (MW 500000) (Dextran blue (MW 500000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin.
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- Molecular Weight: 110000 (Average)
Blue dextran (MW 110000) (Dextran blue (MW 110000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin.
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- Molecular Weight: 40000 (Average)
Blue dextran (MW 40000) (Dextran blue (MW 4000)) is a conjugate of dextran and Cibacron Blue 3G-A ligand, mainly used for purification of human serum albumin.
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- Molecular Weight: 10000 (Average)
Blue dextran (Dextran blue) (MW 10000) is a 10 kDa osmotic dextran. Blue dextran (MW 10000) penetrates all sublayers of the pre-epithelial mucus gel layer in the rat distal colon and is taken up by the nuclei of surface cells in the rat distal colonic mucosa. Blue dextran (MW 10000) is not blocked by the pre-epithelial mucus gel layer of the rat distal colon, which acts as a diffusion barrier.
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- Molecular Weight: 1000000 (Average)
Poly(sodium 4-styrenesulfonate) (MW 1000000) is an ion exchange exchange polyelectrolyte.
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QAE Cross-linked dextran A 25 is a strong anion exchanger.
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