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A2780S

Definition:

A2780S is a human cancer cell line derived from Ovary and associated with Ovarian endometrioid adenocarcinoma and Endometrioid carcinoma of ovary. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. A2780S is used as an in vitro model of Ovarian endometrioid adenocarcinoma and Endometrioid carcinoma of ovary to investigate ERK signaling, p53 signaling, apoptosis, and cytotoxicity.

References:

[1]. Song H, et al. Cisplatin induced apoptosis of ovarian cancer A2780s cells by activation of ERK/p53/PUMA signals. Histology and histopathology. 2018;33(1):73-79. [Content Brief]

[2]. Gamberi T, et al. Proteomic analysis of A2780/S ovarian cancer cell response to the cytotoxic organogold(III) compound Aubipy(c). Journal of proteomics. 2014;103:103-20.

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