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Cat. No.: HY-170600

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Boc-Ala(Me)-H117

Boc-Ala(Me)-H117 is the active control for the target protein ligand H117 (HY-170599) of PROTAC HP211206 (HY-170598).

For research use only. We do not sell to patients.

Formula: C₂₈H₄₄F₂N₆O₇
Molecular Weight:614.68

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Boc-Ala(Me)-H117 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Boc-Ala(Me)-H117 is the active control for the target protein ligand H117 (HY-170599) of PROTAC HP211206 (HY-170598)^[1].

Chemical Information

Molecular Weight 614.68
Formula C₂₈H₄₄F₂N₆O₇
SMILES

O=C(N1[C@H](C(N[C@H](C#N)C[C@H]2C(NCC2)=O)=O)C[C@@H](OC(F)F)C1)[C@H](C(C)(C)C)NC([C@H](C)N(C)C(OC(C)(C)C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sang X, et al. A Chemical Strategy for the Degradation of the Main Protease of SARS-CoV-2 in Cells. J Am Chem Soc. 2023 Dec 20;145(50):27248-27253. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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