Boc-C1-PEG3-C4-OH
Based on 1 Customer Validation
Boc-C1-PEG3-C4-OH is a PROTAC linker, which refers to the Alkyl/ether composition. Boc-C1-PEG3-C4-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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- Reinheit : 95.0%
- CAS. Nr.: 2376724-97-7
- Formel: C16H32O6
- Molecular Weight:320.42
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Alkyl/ether |
Chemical Information
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CAS. Nr. 2376724-97-7
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Appearance Liquid (Density: 1.024 g/cm3)
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Molecular Weight 320.42
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Formel C16H32O6
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)COCCOCCOCCCCCCO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 50 mg/mL (156.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1209 mL | 15.6045 mL | 31.2090 mL | 78.0226 mL |
| 5 mM | 0.6242 mL | 3.1209 mL | 6.2418 mL | 15.6045 mL | |
| 10 mM | 0.3121 mL | 1.5605 mL | 3.1209 mL | 7.8023 mL | |
| 15 mM | 0.2081 mL | 1.0403 mL | 2.0806 mL | 5.2015 mL | |
| 20 mM | 0.1560 mL | 0.7802 mL | 1.5605 mL | 3.9011 mL | |
| 25 mM | 0.1248 mL | 0.6242 mL | 1.2484 mL | 3.1209 mL | |
| 30 mM | 0.1040 mL | 0.5202 mL | 1.0403 mL | 2.6008 mL | |
| 40 mM | 0.0780 mL | 0.3901 mL | 0.7802 mL | 1.9506 mL | |
| 50 mM | 0.0624 mL | 0.3121 mL | 0.6242 mL | 1.5605 mL | |
| 60 mM | 0.0520 mL | 0.2601 mL | 0.5202 mL | 1.3004 mL | |
| 80 mM | 0.0390 mL | 0.1951 mL | 0.3901 mL | 0.9753 mL | |
| 100 mM | 0.0312 mL | 0.1560 mL | 0.3121 mL | 0.7802 mL |
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