2. PROTAC Epigenetics
  3. PROTACs Epigenetic Reader Domain
  4. BRD-SF2

BRD-SF2 is a BRD4-targeted PROTAC degrader (DC50: 17.2 μM) (Blue: VHL ligand, black: linker, pink: BRD4 ligand).

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BRD-SF2

BRD-SF2 화학구조

CAS No. : 3050690-26-8

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BRD-SF2 Related Antibodies

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • Biological Activity

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  • References

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제품 설명

BRD-SF2 is a BRD4-targeted PROTAC degrader (DC50: 17.2 μM) (Blue: VHL ligand, black: linker, pink: BRD4 ligand)[1].

IC50 & Target[1]

BRD4

 

In Vitro

BRD-SF2 (1-75 μM, 18 h) induces endogenous BRD4 degradation in HEK293 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

BRD-SF2 Related Antibodies
분자량

1202.42

화학식

C59H76FN9O13S2
CAS No.
SMILES

O=C1N(C)C=C(C2=NC(C=C(C3CCN(C(COCCOCCOCCNC(C[C@H](NC([C@H]4N(C([C@@H](C5=CC(C)=NO5)C(C)C)=O)C[C@H](S(=O)(F)=O)C4)=O)C6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)CC3)C=C8)=C8N2C(COC)COC)C=C1C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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BRD-SF2 Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

The molarity calculator equation

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Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BRD-SF23050690-26-8PROTACsEpigenetic Reader DomainBRD4 degradationInhibitorinhibitorinhibit

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상품명:
BRD-SF2
Cat. No.:
HY-161368
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