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Cat. No.: HY-184782

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α-Synuclein-IN-19

α-Synuclein-IN-19 is a polyphenolic acid monoamide derivative and an inhibitor of α-synuclein (α-Syn) aggregation. α-Synuclein-IN-19 can be used in Parkinson's disease-related research.

For research use only. We do not sell to patients.

CAS No.: 1026937-99-4
Formula: C₁₅H₁₄N₂O₃
Molecular Weight:270.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

α-Synuclein-IN-19 Chemical Structure

CAS No.: 1026937-99-4

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Biological Activity
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- In Vitro
Chemical Information
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Biological Activity

Description

α-Synuclein-IN-19 is a polyphenolic acid monoamide derivative and an inhibitor of α-synuclein (α-Syn) aggregation. α-Synuclein-IN-19 can be used in Parkinson's disease-related research^[1].

All α-synuclein Isoforms :

In Vitro

α-Synuclein-IN-19 (compound 2e) (30 μM; 72 h) inhibits α-Syn aggregation in vitro with an 88.9% aggregation inhibition ratio^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1026937-99-4
Molecular Weight 270.29
Formula C₁₅H₁₄N₂O₃
SMILES

C(=C/C(NC1=CC=C(N)C=C1)=O)\C2=CC(O)=C(O)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Lü MH, et al. Hybrids of polyphenolic/quinone acids, the potential preventive and therapeutic drugs for PD: Disaggregate α-Syn fibrils, inhibit inclusions, and repair damaged neurons in mice. European journal of medicinal chemistry. 2023 Mar 05;249:115122. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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α-Synuclein-IN-19

All α-synuclein Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

α-Synuclein-IN-19 Related Classifications

HY-184782 Related Classifications