Biotin-PEG3-SH
Based on 1 Customer Validation
Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 1244028-52-1
- Formula: C18H33N3O5S2
- Molecular Weight:435.60
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1244028-52-1
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Appearance Solid
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Molecular Weight 435.60
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Formula C18H33N3O5S2
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Color White to off-white
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SMILES
O=C(NCCOCCOCCOCCS)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
Ethanol : 100 mg/mL (229.57 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 2.2957 mL | 11.4784 mL | 22.9568 mL | 57.3921 mL |
| 5 mM | 0.4591 mL | 2.2957 mL | 4.5914 mL | 11.4784 mL | |
| 10 mM | 0.2296 mL | 1.1478 mL | 2.2957 mL | 5.7392 mL | |
| 15 mM | 0.1530 mL | 0.7652 mL | 1.5305 mL | 3.8261 mL | |
| 20 mM | 0.1148 mL | 0.5739 mL | 1.1478 mL | 2.8696 mL | |
| 25 mM | 0.0918 mL | 0.4591 mL | 0.9183 mL | 2.2957 mL | |
| 30 mM | 0.0765 mL | 0.3826 mL | 0.7652 mL | 1.9131 mL | |
| 40 mM | 0.0574 mL | 0.2870 mL | 0.5739 mL | 1.4348 mL | |
| 50 mM | 0.0459 mL | 0.2296 mL | 0.4591 mL | 1.1478 mL | |
| 60 mM | 0.0383 mL | 0.1913 mL | 0.3826 mL | 0.9565 mL | |
| 80 mM | 0.0287 mL | 0.1435 mL | 0.2870 mL | 0.7174 mL | |
| 100 mM | 0.0230 mL | 0.1148 mL | 0.2296 mL | 0.5739 mL |