Bis-PEG14-acid
Based on 1 Customer Validation
Bis-PEG14-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- Formula: C32H62O18
- Molecular Weight:734.82
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid-Liquid Mixture
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Molecular Weight 734.82
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Formula C32H62O18
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Color White to off-white
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SMILES
OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 350 mg/mL (476.31 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.3609 mL | 6.8044 mL | 13.6088 mL | 34.0219 mL |
| 5 mM | 0.2722 mL | 1.3609 mL | 2.7218 mL | 6.8044 mL | |
| 10 mM | 0.1361 mL | 0.6804 mL | 1.3609 mL | 3.4022 mL | |
| 15 mM | 0.0907 mL | 0.4536 mL | 0.9073 mL | 2.2681 mL | |
| 20 mM | 0.0680 mL | 0.3402 mL | 0.6804 mL | 1.7011 mL | |
| 25 mM | 0.0544 mL | 0.2722 mL | 0.5444 mL | 1.3609 mL | |
| 30 mM | 0.0454 mL | 0.2268 mL | 0.4536 mL | 1.1341 mL | |
| 40 mM | 0.0340 mL | 0.1701 mL | 0.3402 mL | 0.8505 mL | |
| 50 mM | 0.0272 mL | 0.1361 mL | 0.2722 mL | 0.6804 mL | |
| 60 mM | 0.0227 mL | 0.1134 mL | 0.2268 mL | 0.5670 mL | |
| 80 mM | 0.0170 mL | 0.0851 mL | 0.1701 mL | 0.4253 mL | |
| 100 mM | 0.0136 mL | 0.0680 mL | 0.1361 mL | 0.3402 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Bis-PEG14-acid Related Classifications
HY-141022 Related Classifications
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