Pole - polymerase (DNA directed), epsilon Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18973

Summary

Predicted to enable DNA binding activity; catalytic activity, acting on DNA; and chromatin binding activity. Predicted to be involved in DNA metabolic process and G1/S transition of mitotic cell cycle. Predicted to act upstream of or within DNA repair. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of epsilon DNA Polymerase complex. Is expressed in nervous system. Human ortholog(s) of this gene implicated in colorectal Cancer. Orthologous to human POLE (DNA Polymerase epsilon, catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]

Pole Products (1)

mRNA Protein Name
NM_011132.2 NP_035262.2 DNA polymerase epsilon catalytic subunit A
Protein Preferred Names Protein Names

DNA polymerase epsilon catalytic subunit A

  • 3'-5' exodeoxyribonuclease

  • DNA polymerase II subunit A

  • DNA-directed DNA polymerase epsilon

  • pol-epsilon

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153066 VLS-1272 99.63% Unkown
HY-121908 FCPT Inhibitor / Unkown
HY-D1737 RADA / Unkown
HY-RS10825 POLE Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10826 POLE2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10827 POLE3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10828 POLE4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-B0824A (1R)-cis-Bifenthrin / Unkown
HY-RS17692 Pole Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22734 Pole2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24154 Pole Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29248 Pole2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pole NCBI NCBI:5426