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Cat. No.: HY-101686

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LM-1484

LM-1484 is an antagonist of CysLT1 receptor and displays a higher affinity for ³H-LTC4 sites.

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CAS No.: 197506-02-8
Formule: C₂₈H₂₄N₄O₃
Masse moléculaire:464.52

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

LM-1484 Chemical Structure

CAS No.: 197506-02-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
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Description

LM-1484 is an antagonist of CysLT1 receptor and displays a higher affinity for ³H-LTC4 sites.

IC₅₀ & Target

^[1]

CysLT₁

LTC₄

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In Vitro

LM-1484 (10 μM) induces the dissociation of ³H-LTD4, and is able to displace ³H-LTC4 from its binding sites^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 197506-02-8
Masse moléculaire 464.52
Formule C₂₈H₂₄N₄O₃
SMILES

O=C1C=C(C2=NN=NN2)OC3=C(/C=C/C4=CC=C(OCCCCC5=CC=CC=C5)C=C4)C=CC=C13
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ravasi S, et al. Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma. Biochem Pharmacol. 2002 Apr 15;63(8):1537-46. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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LM-1484

Voir tous les produits spécifiques à Isoform Leukotriene Receptor

Activité biologique

Description

IC50 & Target

In Vitro

Chemical Information

Pureté et documentation

Références

Calculators

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LM-1484 Related Classifications

HY-101686 Related Classifications

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