A-412997
Based on 1 publication(s) in Google Scholar
A-412997 is a selective Dopamine D4 agonist with Ki values of 12 and 7.9 nM for the rat and human receptors. A-412997 improves short term memory and cognitive properties in rodent models.
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- CAS No.: 630116-49-3
- Formule: C19H23N3O
- Masse moléculaire:309.41
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Publications Citing Use of MedChemExpress (MCE) A-412997
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
14 nM
Compound: 5k
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Agonist activity at human D4.4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPR
Agonist activity at human D4.4 receptor in HEK293 cells coexpressing G-alpha-qo5 by FLIPR
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[PMID: 17149874] |
Chemical Information
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CAS No. 630116-49-3
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Masse moléculaire 309.41
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Formule C19H23N3O
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SMILES
O=C(NC1=CC=CC(C)=C1)CN2CCC(C3=NC=CC=C3)CC2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Br J Cancer
DRD4 promotes chemo-resistance and cancer stem cell-like phenotypes by mediating the activation of the Akt/β-catenin signaling axis in liver cancer. [Abstract]2024 Oct;131(7):1212-1223. PMID: 39174739
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A-412997 Related Classifications
HY-129103 Related Classifications
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