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Cat. No.: HY-147505

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Antitubercular agent-21

Antitubercular agent-21 (Compound 15) is an antitubercular agent with an MIC of o.4 µg/mL against M. tuberculosis H₃₇R_v. Antitubercular agent-21 exhibits lower activity against other microorganism such as bacteria gram-positive, gram-negative or fungi. Antitubercular agent-21 shows low cytotoxicity.

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CAS No.: 2412142-93-7
Formule: C₁₅H₂₂N₆OS
Masse moléculaire:334.44

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Antitubercular agent-21 Chemical Structure

CAS No.: 2412142-93-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
B16-F10	IC₅₀	10.98 μg/mL Compound: 15	Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 32061963]
NHDF	IC₅₀	36.18 μg/mL Compound: 15	Cytotoxicity against human NHDF cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human NHDF cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 32061963]

Chemical Information

CAS No. 2412142-93-7
Masse moléculaire 334.44
Formule C₁₅H₂₂N₆OS
SMILES

N/C(C1=NC=CC(N2CCCC2)=C1)=N\NC(N3CCOCC3)=S
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Krause M, et al. 4-Substituted picolinohydrazonamides as a new class of potential antitubercular agents. Eur J Med Chem. 2020 Mar 15;190:112106. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculateur de dilution

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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