Calcicludine
Calcicludine is a protein toxin from the venom of the green mamba that inhibits high-voltage-activated calcium channel, especially L-type calcium channel.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 178036-64-1
- Formule: C321H476N86O78S6
- Masse moléculaire:6980.13
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform Calcium Channel
More
Activité biologique
|
L-type calcium channel 88 nM (IC50) |
Chemical Information
-
CAS No. 178036-64-1
-
Masse moléculaire 6980.13
-
Formule C321H476N86O78S6
-
Sequence
Trp-Gln-Pro-Pro-Trp-Tyr-Cys-Lys-Glu-Pro-Val-Arg-Ile-Gly-Ser-Cys-Lys-Lys-Gln-Phe-Ser-Ser-Phe-Tyr-Phe-Lys-Trp-Thr-Ala-Lys-Lys-Cys-Leu-Pro-Phe-Leu-Phe-Ser-Gly-Cys-Gly-Gly-Asn-Ala-Asn-Arg-Phe-Gln-Thr-Ile-Gly-Glu-Cys-Arg-Lys-Lys-Cys-Leu-Gly-Lys (Disulfide bridge: Cys7-Cys57; Cys16-Cys40; Cys32-Cys53)
-
Sequence Shortening
WQPPWYCKEPVRIGSCKKQFSSFYFKWTAKKCLPFLFSGCGGNANRFQTIGECRKKCLGK (Disulfide bridge: Cys7-Cys57; Cys16-Cys40; Cys32-Cys53)
-
Structure Classification
-
Initial Source
Ceratogyrus cornuatus
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. H Schweitz, et al. Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons. Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):878-82. [Content Brief]
[2]. S C Stotz, et al. Block of Voltage-dependent Calcium Channel by the Green Mamba Toxin Calcicludine. J Membr Biol. 2000 Mar 15;174(2):157-65. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz