2829263-20-7
2829263-20-7
Chemical Structure
FPR2 agonist 2
- CAS No.: 2829263-20-7
- Formula:C25H20F2N4O2
- Molecular Weight:446.45
IUPAC Name: isopropyl 3,3-difluoro-1-(hydroxymethyl)cyclobutane-1-carboxylate
InChIKey: KCNMTQVKKFREAN-QFIPXVFZSA-N
SMILES: FC1=CC=C(C=C1)NC(N[C@H](C(N2CCC3=C2C=CC(F)=C3)=O)CC4=CC=C(C=C4)C#N)=O
Biological Activity: FPR2 agonist 2 is a potent and CNS-penetrant FPR2 agonist with an EC50 of 0.13 μM, 1.1 μM for FPR2 and FPR1, respectively. FPR2 agonist 2 inhibits the production of pro-inflammatory cytokines, counterbalances the changes in mitochondrial function, and inhibits caspase-3 activity[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
FPR2 agonist 2 | 98.51% | FPR2 agonist 2 is a potent and CNS-penetrant FPR2 agonist with an EC50 of 0.13 μM, 1.1 μM for FPR2 and FPR1, respectively. FPR2 agonist 2 inhibits the production of pro-inflammatory cytokines, counterbalances the changes in mitochondrial function, and inhibits caspase-3 activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.91
HY-155335FPR2 agonist 3 -
Similarity Score 0.71
HY-178011IDO1-IN-28 -
Similarity Score 0.65
HY-184654MR-39 -
Similarity Score 0.62
HY-178024IDO1-IN-29 -
Similarity Score 0.54
HY-175196P2X7 receptor antagonist-6 -
Similarity Score 0.51
HY-W414109ID110460002 -
Similarity Score 0.50
HY-134445N-Benzoyl-L-tyrosine p-nitroanilide -
Similarity Score 0.50
HY-B1493RBentiromide (Standard) -
Similarity Score 0.49
HY-116071Autophagy-IN-3 -
Explore the MedChemAI to find more analogs
