ClpP1P2-IN-1
ClpP1P2-IN-1 is a protease inhibitor targeting ClpP1P2 of Mycobacterium tuberculosis, with a Ki value of 0.04 μM. ClpP1P2-IN-1 inhibits the growth of Mycobacterium tuberculosis and shows low cytotoxicity against mammalian kidney cells. ClpP1P2-IN-1 can be used in the research of tuberculosis.
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- CAS No.: 3069900-75-7
- Formule: C26H27F5N4O4S2
- Masse moléculaire:618.64
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
ClpP1P2-IN-1 (ClpP-1697) inhibits growth of Mycobacterium tuberculosis strain H37Rv with an average MIC of 0.11 μg/mL in Middlebrook 7H12 medium without catalase[1].
ClpP1P2-IN-1 has no significant cytotoxicity against Vero green monkey kidney cells, with an IC50 >20 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3069900-75-7
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Masse moléculaire 618.64
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Formule C26H27F5N4O4S2
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SMILES
FCC1=C(C2=NC=C(C(N[C@@H](CCC(O)C)C(N[C@@H](CCCC(F)(F)F)C(C3=NC=CS3)=O)=O)=O)S2)C=C(C=C1)F
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)