DA 1686
DA 1686 is an orally active naphthalene derivative that induces bradycardia and mild hypotension. DA 1686 can be used in the study of arrhythmias.
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- CAS No.: 13071-27-7
- Formule: C23H32N2O2
- Masse moléculaire:368.51
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
DA 1686 reduces aconitine-induced tachycardia and responsiveness to increased electrical stimulation in isolated guinea-pig auricles[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
DA 1686 (20 mg/kg; i.v.; slow infusion) protects anaesthetized dogs from Adrenaline (HY-B0447)-induced death during benzol inhalation[1].
DA 1686 protects rats from arrhythmia induced by intravenous administration of 34 μg/kg Aconitine[1].
DA 1686 delays the onset of Ouabain (HY-B1457)-induced arrhythmia, ventricular fibrillation, and cardiac arrest in guinea-pigs[1].
DA 1686 reduces tachycardia induced by 10 days of daily 0.2 mg Thyroxine (HY-18341) administration in rabbits[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Dog[1]
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Dosage:20 mg/kg
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Administration:i.v.; slow infusion
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Result:Protected anaesthetized dogs from death induced by rapid intravenous adrenaline administration during benzol inhalation.
Chemical Information
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CAS No. 13071-27-7
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Masse moléculaire 368.51
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Formule C23H32N2O2
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SMILES
N1(CCC(CCN2CCOCC2)C3=CC=CC4=C3C=CC=C4)CCOCC1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DA 1686 Related Classifications
HY-120730 Related Classifications
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