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Cat. No.: HY-155288

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DosatiLink-1

DosatiLink-1 is an Abelson murine leukemia (ABL) enzyme inhibitor.

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CAS No.: 2941512-37-2
Formule: C₆₉H₉₃Cl₂F₂N₁₃O₁₇S
Masse moléculaire:1517.52

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

DosatiLink-1 Chemical Structure

CAS No.: 2941512-37-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

DosatiLink-1 is an Abelson murine leukemia (ABL) enzyme inhibitor^[1].

Voir tous les produits spécifiques à Isoform Bcr-Abl :

Abl
Bcr-Abl

Cellular Effect

Cell Line	Type	Value	Description	References
K562	EC₅₀	>300 nM Compound: Dosati Link-1	Antiproliferative activity against human K562 cells expressing ABL T315I mutant assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay Antiproliferative activity against human K562 cells expressing ABL T315I mutant assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay	[PMID: 37849551]
K562	EC₅₀	2.47 nM Compound: Dosati Link-1	Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay	[PMID: 37849551]

Chemical Information

CAS No. 2941512-37-2
Masse moléculaire 1517.52
Formule C₆₉H₉₃Cl₂F₂N₁₃O₁₇S
SMILES

O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(C1CCN(C2=C(C3=CC=NN3)C=C(C(NC4=CC=C(OC(F)(Cl)F)C=C4)=O)C=N2)CC1)=O)N5CCN(C6=CC(NC7=NC=C(C(NC8=C(Cl)C=CC=C8C)=O)S7)=NC(C)=N6)CC5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Robert B. Kargbo. Expanding the Chemical Space: New Approach to Cell-Permeable Drugs. ACS Med. Chem. Lett. 2023, 14, 10, 1329-1330.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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