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Cat. No.: HY-149929

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EBL-3183

EBL-3183, an indole-2-carboxylate, is a potent metallo-β-lactamase (MBL) inhibitor. EBL-3183 is reversibly binding, non-covalent, competitive NDM-1 inhibitor with a pIC₅₀ of 7.7.

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CAS No.: 2872672-18-7
Formule: C₂₅H₂₇FN₄O₆S
Masse moléculaire:530.57

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

EBL-3183 Chemical Structure

CAS No.: 2872672-18-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

EBL-3183, an indole-2-carboxylate, is a potent metallo-β-lactamase (MBL) inhibitor. EBL-3183 is reversibly binding, non-covalent, competitive NDM-1 inhibitor with a pIC₅₀ of 7.7^[1].

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Chemical Information

CAS No. 2872672-18-7
Masse moléculaire 530.57
Formule C₂₅H₂₇FN₄O₆S
SMILES

C[C@H](N1C[C@]2(OC1=O)C[C@@H](C2)CN)C3=CC=CC4=C3NC(C(O)=O)=C4C5=CC=C(C(F)=C5)NS(C)(=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Jürgen Brem, et al. Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors. Nat Chem. 2022 Jan;14(1):15-24. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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EBL-3183

Voir tous les produits spécifiques à Isoform Beta-lactamase