GDC-0570
GDC-0570 is a novel, potent, selective, orally active pan-PIM inhibitor. GDC-0570 demonstrates synergistic antitumor efficacy when combined with Sotorasib (HY-114277) in acquired KRASis-resistant NSCLC.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1586041-58-8
- Formule: C20H20F3N5O2S
- Masse moléculaire:451.47
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1586041-58-8
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Masse moléculaire 451.47
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Formule C20H20F3N5O2S
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SMILES
O=C(C1=CSC(C2=C(C=CC=C2F)F)=N1)NC3=C([C@@H]4CC[C@H]([C@@H](CO4)F)N)N(N=C3)C
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Synonyms
NB004
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GDC-0570 Related Classifications
HY-171193 Related Classifications
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