MYDGF - myeloid derived growth factor Gene

Also Known as IL25; IL27; SF20; IL27w; C19orf10; R33729_1; EUROIMAGE1875335

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56005

About MYDGF

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:4,657,545-4,670,342 (from NCBI)

This gene has 4 transcripts (splice variants) and 183 orthologues. Ubiquitous expression in colon (RPKM 37.2), prostate (RPKM 33.6) and 25 other tissues.

Summary

The protein encoded by this gene was previously thought to support proliferation of lymphoid cells and was considered an interleukin. However, this activity has not been reproducible and the function of this protein is currently unknown. [provided by RefSeq, Jul 2008]

MYDGF Products (1)

mRNA Protein Name
NM_019107.4 NP_061980.1 myeloid-derived growth factor precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence Références Source
involved in positive regulation of angiogenesis IDA
IDA: Inferred from direct assay
25581518 GOA
involved in positive regulation of endothelial cell proliferation IDA
IDA: Inferred from direct assay
25581518 GOA
Cellular Component GO Annotation Evidence Références Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
29954947 GOA
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
29954947 GOA
located in extracellular space IDA
IDA: Inferred from direct assay
25581518 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MYDGF Protein Structure

UPF0556

UPF0556: Uncharacterised protein family UPF0556 (16 - 173)

  • 0
  • 100
  • 173 a.a.
Protein Preferred Names Protein Names

myeloid-derived growth factor

  • UPF0556 protein C19orf10

MYDGF Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
MYDGF Q969H8 ACOT13 Homo sapiens Q9NPJ3
Validated Y2H
32296183
Intra
MYDGF Q969H8 ACOT13 Homo sapiens Q9NPJ3
Y2H Prey Pooling
32296183
Intra
MYDGF Q969H8 ACOT13 Homo sapiens Q9NPJ3
Y2H Array
32296183
Intra
MYDGF Q969H8 LCN2 Homo sapiens P80188
Y2H Prey Pooling
32296183
Intra
MYDGF Q969H8 LCN2 Homo sapiens P80188
Y2H Array
32296183
Intra
MYDGF Q969H8 HPCA Homo sapiens P84074
Y2H Array
32296183
Intra
MYDGF Q969H8 HPCA Homo sapiens P84074
Y2H Prey Pooling
32296183
Intra
MYDGF Q969H8 LDB2 Homo sapiens O43679
Y2H Prey Pooling
32296183
Intra
MYDGF Q969H8 LDB2 Homo sapiens O43679
Y2H Array
32296183
Intra
MYDGF Q969H8 SGTA Homo sapiens O43765
Y2H Prey Pooling
32296183
Intra
MYDGF Q969H8 SGTA Homo sapiens O43765
Y2H Array
32296183
Intra
MYDGF Q969H8 SGTA Homo sapiens O43765
Validated Y2H
25416956
Intra
MYDGF Q969H8 EIF3F Homo sapiens O00303
Y2H Prey Pooling
32296183
Intra
MYDGF Q969H8 EIF3F Homo sapiens O00303
Y2H Array
32296183
Intra
MYDGF Q969H8 UBQLN1 Homo sapiens Q9UMX0
Validated Y2H
32296183
Intra
MYDGF Q969H8 UBQLN1 Homo sapiens Q9UMX0
Y2H Array
32296183
Intra
MYDGF Q969H8 UBQLN1 Homo sapiens Q9UMX0
Y2H Prey Pooling
32296183
Intra
MYDGF Q969H8 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
Intra
MYDGF Q969H8 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra
MYDGF Q969H8 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra
MYDGF Q969H8 SGTB Homo sapiens Q96EQ0
Y2H Array
32296183
Intra
MYDGF Q969H8 SGTB Homo sapiens Q96EQ0
Validated Y2H
32296183
Intra
MYDGF Q969H8 SGTB Homo sapiens Q96EQ0
Y2H Prey Pooling
32296183
Intra
MYDGF Q969H8 HPCAL1 Homo sapiens P37235
Y2H Prey Pooling
32296183
Intra
MYDGF Q969H8 HPCAL1 Homo sapiens P37235
Y2H Array
32296183
Intra
MYDGF Q969H8 HPCAL1 Homo sapiens P37235
MAPPIT
32296183
Intra
MYDGF Q969H8 NCALD Homo sapiens P61601
Y2H Prey Pooling
32296183
Intra
MYDGF Q969H8 NCALD Homo sapiens P61601
Y2H Array
32296183
Intra
MYDGF Q969H8 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
Intra
MYDGF Q969H8 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
Intra
MYDGF Q969H8 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
Intra
MYDGF Q969H8 PDIA5 Homo sapiens Q14554
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant MYDGF Proteins

Cat. No. Nom du produit Accession Pureté
HY-P70581 MYDGF Protein, Human (His) Q969H8 (S33-L173) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700641 SF20/MYDGF Protein, Human (HEK293, His) Q969H8 (V32-L173) ≥ 95%, as determined by reducing SDS-PAGE.

MYDGF Anticorps

Cat. No. Nom du produit Application Reactivity
HY-P82783 SF20 Antibody (YA2528) WB, FC Human
HY-P82783A SF20 Antibody (YA2528)(PBS only) WB, FC Human

Related Diseases

Diseases Alias
Myocardial Infarction

  • Heart Attack

  • Myocardial Infarction, Susceptibility To

  • Myocardial Infarction 1

  • Myocardial Infarction, Protection Against

  • Myocardial Infarction, Decreased Susceptibility To

  • Myocardial Infarction, Decreased

  • Myocardial Infarct

  • MCI1

  • Premature Myocardial Infarction

  • Myocardial Infarction, Susceptibility To, Type 1
Heinz Body Anemias

  • Heinz Body Anemia

  • Heinz Body Anemias, Alpha-

  • HEIBAN

  • Anemia, Heinz Body

  • Acquired Heinz Body Anemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS08889 MYDGF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174576 Human MYDGF mRNA / Unkown
HY-RS17706 Mydgf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24171 Mydgf Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MYDGF MGD MGI:2156020
Bos taurus MYDGF VGNC VGNC:31790
Felis catus MYDGF VGNC VGNC:63673
Rattus norvegicus MYDGF RGD RGD:1589603
Canis familiaris MYDGF VGNC VGNC:43532
Others MYDGF NCBI