GZ-11608
GZ-11608 is a potent and selective vesicular monoamine transporter-2 (VMAT2) inhibitor with high affinity (Ki = 25 nM). GZ-11608 decreases methamphetamine-induced dopamine release from isolated synaptic vesicles from brain dopaminergic neurons. GZ-11608 exhibits rapid brain penetration and without neurotoxicity. GZ-11608 can be used for the research of methamphetamine use disorder.
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- CAS No.: 2141974-01-6
- Formule: C19H25NO
- Masse moléculaire:283.41
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Ki: 25 nM (VMAT2)[1]
Chemical Information
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CAS No. 2141974-01-6
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Masse moléculaire 283.41
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Formule C19H25NO
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SMILES
C[C@H](NCCCC1=CC=C(OC)C=C1)CC2=CC=CC=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GZ-11608 Related Classifications
HY-152171 Related Classifications
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