HDAC-IN-55
Based on 1 Customer Validation
HDAC-IN-55(8j) is a small molecular compound that can increase the expression of E-cadherin and inhibit the proliferation of cancer cells.
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- Pureté: 98.02%
- CAS No.: 1268674-16-3
- Formule: C17H17N3O3
- Masse moléculaire:311.34
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| SW-620 | EC50 |
4.7 μM
Compound: 1
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Restoration of e-cadherin expression in human SW620 cells by in-cell-western assay
Restoration of e-cadherin expression in human SW620 cells by in-cell-western assay
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[PMID: 26299347] |
HDAC-IN-55(8j) acts on SW620 cell line and H520 cell line with the EC50 values of 4.47 and 1.61 μM, respectively[1].
HDAC-IN-55(8j) (10 μM, 24 h) can increase the expression of E-cadherin in SW620 cells and inhibit the proliferation of SW620 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1268674-16-3
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Appearance Solid
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Masse moléculaire 311.34
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Formule C17H17N3O3
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Color Light yellow to yellow
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SMILES
O=C(C1=NOC(C2=CC=CO2)=C1)NCCCCC3=CC=NC=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 100 mg/mL (321.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2119 mL | 16.0596 mL | 32.1192 mL | 80.2981 mL |
| 5 mM | 0.6424 mL | 3.2119 mL | 6.4238 mL | 16.0596 mL | |
| 10 mM | 0.3212 mL | 1.6060 mL | 3.2119 mL | 8.0298 mL | |
| 15 mM | 0.2141 mL | 1.0706 mL | 2.1413 mL | 5.3532 mL | |
| 20 mM | 0.1606 mL | 0.8030 mL | 1.6060 mL | 4.0149 mL | |
| 25 mM | 0.1285 mL | 0.6424 mL | 1.2848 mL | 3.2119 mL | |
| 30 mM | 0.1071 mL | 0.5353 mL | 1.0706 mL | 2.6766 mL | |
| 40 mM | 0.0803 mL | 0.4015 mL | 0.8030 mL | 2.0075 mL | |
| 50 mM | 0.0642 mL | 0.3212 mL | 0.6424 mL | 1.6060 mL | |
| 60 mM | 0.0535 mL | 0.2677 mL | 0.5353 mL | 1.3383 mL | |
| 80 mM | 0.0401 mL | 0.2007 mL | 0.4015 mL | 1.0037 mL | |
| 100 mM | 0.0321 mL | 0.1606 mL | 0.3212 mL | 0.8030 mL |
HDAC-IN-55 Related Classifications
HY-153607 Related Classifications
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