PAD3-IN-1
PAD3-IN-1 (compound 14b) is an inhibitor of protein arginine deiminase (PAD) and is more than 10-fold more selective for PAD3 than PAD 1, 2, and 4. The IC50 values of PAD3-IN-1 for PAD 1, 2, 3, and 4 are 120, 27.5, 4.5, and 30.5 μM, respectively. And PAD3 is a PAD isoform associated with neurodegenerative responses to spinal cord injury, and PAD3-IN-1 could be used to study PAD-related neurological diseases.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1671088-84-8
- Formule: C21H22Cl2N4O2
- Masse moléculaire:433.33
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
Description
IC50 & Target
IC50: 120 μM (PAD1)[1]. IC50: 27.5 μM (PAD2)[1]. IC50: 4.5 μM (PAD3)[1]. IC50: 30.5 μM (PAD4)[1].
Chemical Information
-
CAS No. 1671088-84-8
-
Masse moléculaire 433.33
-
Formule C21H22Cl2N4O2
-
SMILES
N=C(NCCCC(C(N1CC2=CC(C3=CC=CC=C3Cl)=CC=C2)=O)NC1=O)CCl
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PAD3-IN-1 Related Classifications
HY-139088 Related Classifications
Powered by Bioz