(+)-JQ1-OH
(+)-JQ1-OH is the major metabolite of (+)-JQ1(HY-13030). (+)-JQ-1 (JQ1) is a potent, specific, and reversible BET bromodomain inhibitor, with IC50s of 77 and 33 nM for the first and second bromodomain (BRD4(1/2)). (+)-JQ-1 also activates autophagy.
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- Formule: C23H25ClN4O3S
- Masse moléculaire:472.99
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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BET |
Chemical Information
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Masse moléculaire 472.99
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Formule C23H25ClN4O3S
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SMILES
OCC(S1)=C(C)C2=C1N3C([C@H](CC(OC(C)(C)C)=O)N=C2C4=CC=C(Cl)C=C4)=NN=C3C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)