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Cat. No.: HY-150547

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RSV-IN-6

RSV-IN-6 (Compound 53) is an anti-RSV agent targeting M2-1 protein with EC₅₀ values of 4.4 μM and 1.3 μM against RSV-A and RSV-B strain, respectively.

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CAS No.: 2415152-41-7
Formule: C₁₉H₁₉N₃S₃
Masse moléculaire:385.57

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

RSV-IN-6 Chemical Structure

CAS No.: 2415152-41-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

RSV-IN-6 (Compound 53) is an anti-RSV agent targeting M2-1 protein with EC₅₀ values of 4.4 μM and 1.3 μM against RSV-A and RSV-B strain, respectively^[1].

IC₅₀ & Target

EC₅₀: 1.3 μM (RSV-B), 4.4 μM (RSV-A)^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
HEp-2	CC₅₀	>100 μM Compound: 53	Cytotoxicity against human Hep2 cells assessed as reduction in cell viability measured after 5 days by MTS assay Cytotoxicity against human Hep2 cells assessed as reduction in cell viability measured after 5 days by MTS assay	[PMID: 32143992]
HEp-2	EC₅₀	1.3 μM Compound: 53	Antiviral activity against Respiratory syncytial virus B infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis Antiviral activity against Respiratory syncytial virus B infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis	[PMID: 32143992]
HEp-2	EC₅₀	4.4 μM Compound: 53	Antiviral activity against Respiratory syncytial virus A strain Long infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis Antiviral activity against Respiratory syncytial virus A strain Long infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect after 5 days by microscopic analysis	[PMID: 32143992]

Chemical Information

CAS No. 2415152-41-7
Masse moléculaire 385.57
Formule C₁₉H₁₉N₃S₃
SMILES

S=C(N1CCN(C2=CC=CC=C2)CC1)SCC3=NC4=CC=CC=C4S3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ferla S, et al. Rational modifications, synthesis and biological evaluation of new potential antivirals for RSV designed to target the M2-1 protein. Bioorg Med Chem. 2020 Apr 15;28(8):115401. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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