Sporothriolide
Sporothriolide is a metabolite produced by Nodulisporium sp. A21. Sporothriolide has potently antifungal against R. solani and S. sclerotiorum, with EC50 values of 11.6 μM and 10.7 μM, respectively. Sporothriolide inhibits conidium germination of Magnaporthe oryzae in vitro and in vivo.
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- CAS No.: 154799-92-5
- Formule: C13H18O4
- Masse moléculaire:238.28
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
7.1 μM
Compound: 1
|
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 29043802] |
| MCF7 | IC50 |
4 μM
Compound: 1
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 29043802] |
| PC-3 | IC50 |
6.4 μM
Compound: 1
|
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
|
[PMID: 29043802] |
Chemical Information
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CAS No. 154799-92-5
-
Masse moléculaire 238.28
-
Formule C13H18O4
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SMILES
O=C(O[C@]1([H])[C@@]2([H])C(O[C@@H]1CCCCCC)=O)C2=C
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Structure Classification
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Initial Source
Nodulisporium sp. A21
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)