Synephrine hemitartrate
Based on 3 publication(s) in Google Scholar
Synephrine (Oxedrine) hemitartrate, an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine hemitartrate is a sympathomimetic compound and can be used for weight loss.
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- CAS No.: 16589-24-5
- Formule: C9H13NO2.1/2C4H6O6
- Masse moléculaire:242.26
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Stockage:
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
Description
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Portal vein ligation (PVL) or bile duct ligation (BDL) rats[2].
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Dosage:1 mg/kg per 12 hours
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Administration:Oral gavage; for 8 days
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Result:The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index were significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance were enhanced.
Chemical Information
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CAS No. 16589-24-5
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Masse moléculaire 242.26
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Formule C9H13NO2.1/2C4H6O6
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SMILES
OC(C1=CC=C(O)C=C1)CNC.O=C(O)[C@H](O)[C@@H](O)C(O)=O.[1/2]
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Synonyms
Oxedrine hemitartrate
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (3)
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Journal Impact Factor
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Most Recent
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Arch Toxicol
Quantitative in vitro-to-in vivo extrapolation of human adrenergic and trace amine-associated receptor 1 potencies of pre-workout supplement ingredients using physiologically based kinetic modelling-based reverse dosimetry. [Abstract]2025 May;99(5):1999-2021. PMID: 40178592 -
Toxicology
In vitro inhibition of monoamine transport by amphetamine-like pre-workout supplement ingredients. [Abstract]2026 Mar 6:154442. PMID: 41796714 -
Cardiovasc Toxicol
Potential Cardiovascular Risks of Phenethylamine Analogues in Food Supplements: Evidence from Vasocontraction of Rat Artery Segments. [Abstract]2026 Apr 4;26(4):36. PMID: 41934574
Pureté et documentation
Références
[1]. Thomas JE, et al. STEMI in a 24-year-old man after use of a synephrine-containing dietary supplement: a case report and review of the literature. Tex Heart Inst J. 2009;36(6):586-90. [Content Brief]
[2]. Huang YT, et al. Hemodynamic effects of synephrine treatment in portal hypertensive rats. Jpn J Pharmacol. 2001 Feb;85(2):183-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Synephrine hemitartrate Related Classifications
HY-N0132B Related Classifications
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