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Cat. No.: HY-N10082

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Trigoxyphin A

Trigoxyphin A is a oxygenated daphnane-type diterpenoids. Trigoxyphin A exhibites strong cytotoxic activity against HL60 and A549 with IC₅₀s of 0.27 and 7.5 μM, respectively.

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CAS No.: 1236874-00-2
Formule: C₃₄H₃₄O₉
Masse moléculaire:586.63

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (281 KB)

Trigoxyphin A Chemical Structure

CAS No.: 1236874-00-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Trigoxyphin A is a oxygenated daphnane-type diterpenoids. Trigoxyphin A exhibites strong cytotoxic activity against HL60 and A549 with IC₅₀s of 0.27 and 7.5 μM, respectively^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>10 μM Compound: 8	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay	[PMID: 21192108]
A549	IC₅₀	7.5 μM Compound: 1	Cytotoxicity against human A549 cells after 72 hrs by SRB assay Cytotoxicity against human A549 cells after 72 hrs by SRB assay	[PMID: 20593838]
Bel-7402	IC₅₀	>10 μM Compound: 1	Cytotoxicity against human Bel7402 cells after 72 hrs by SRB assay Cytotoxicity against human Bel7402 cells after 72 hrs by SRB assay	[PMID: 20593838]
HL-60	IC₅₀	>10 μM Compound: 8	Cytotoxicity against human HL60 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human HL60 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 21192108]
HL-60	IC₅₀	0.27 μM Compound: 1	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 20593838]
MCF7	IC₅₀	>10 μM Compound: 8	Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by SRB assay	[PMID: 21192108]

Chemical Information

CAS No. 1236874-00-2
Masse moléculaire 586.63
Formule C₃₄H₃₄O₉
SMILES

C[C@H]1[C@]23[C@]([C@H]4[C@](O4)([C@H]([C@]5([C@@]3([H])C=C(C5=O)C)O)O)C)([H])[C@]6([H])[C@]([C@H]1OC(C7=CC=CC=C7)=O)(O[C@](O6)(C8=CC=CC=C8)O2)C(C)=C
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (281 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lin BD, et al. Trigoxyphins A-G: diterpenes from Trigonostemon xyphophylloides. J Nat Prod. 2010 Jul 23;73(7):1301-5. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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