TS-IN-6
TS-IN-6 (Compound 10) is a thymidylate synthase (TS) inhibitor with an IC50 value of 0.54 μM, demonstrating significant antiproliferative activity. TS-IN-6 induces G1 phase cell cycle arrest and apoptosis (marked by substantial increases in both early and late apoptotic rates) and shows potential for research on cancers such as colon, breast, and liver cancers.
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- Formule: C29H22F2N6OS
- Masse moléculaire:540.59
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
IC50: 0.54 μM (TS)[1].
Chemical Information
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Masse moléculaire 540.59
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Formule C29H22F2N6OS
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SMILES
CC1=CC=CC=C1N2C(SCC3=CN(C4=CC=C(F)C=C4F)N=N3)=NN=C2COC5=CC=C6C=CC=CC6=C5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)