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  3. Canagliflozin impurity 12

Canagliflozin impurity 12 is an impurity of Canagliflozin (HY-10451).

For research use only. We do not sell to patients.

Canagliflozin impurity 12

Canagliflozin impurity 12 Chemical Structure

CAS No. : 1823966-94-4

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Description

Canagliflozin impurity 12 is an impurity of Canagliflozin (HY-10451).

Molecular Weight

328.17

Formula

C12H9IOS

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CC1=C(C(C2=CC=CS2)=O)C=C(I)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (304.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0472 mL 15.2360 mL 30.4720 mL
5 mM 0.6094 mL 3.0472 mL 6.0944 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0472 mL 15.2360 mL 30.4720 mL 76.1800 mL
5 mM 0.6094 mL 3.0472 mL 6.0944 mL 15.2360 mL
10 mM 0.3047 mL 1.5236 mL 3.0472 mL 7.6180 mL
15 mM 0.2031 mL 1.0157 mL 2.0315 mL 5.0787 mL
20 mM 0.1524 mL 0.7618 mL 1.5236 mL 3.8090 mL
25 mM 0.1219 mL 0.6094 mL 1.2189 mL 3.0472 mL
30 mM 0.1016 mL 0.5079 mL 1.0157 mL 2.5393 mL
40 mM 0.0762 mL 0.3809 mL 0.7618 mL 1.9045 mL
50 mM 0.0609 mL 0.3047 mL 0.6094 mL 1.5236 mL
60 mM 0.0508 mL 0.2539 mL 0.5079 mL 1.2697 mL
80 mM 0.0381 mL 0.1905 mL 0.3809 mL 0.9523 mL
100 mM 0.0305 mL 0.1524 mL 0.3047 mL 0.7618 mL
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Canagliflozin impurity 12 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Canagliflozin impurity 12
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HY-I0535
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