Cannabisin F
Based on 1 Customer Validation
Cannabisin F is a SIRT1 modulator. Cannabisin F, as a hempseed lignanamide, can be used for the research of anti-inflammatory and anti-oxidative. Cannabisin F may be a potential agent of neurodegenerative diseases as modulators of SIRT1/NF-κB and Nrf2.
For research use only. We do not sell to patients.
- Purity: 96.0%
- CAS No.: 163136-19-4
- Formula: C36H36N2O8
- Molecular Weight:624.68
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SIRT1[1]
Cannabisin F (0~15 μM; 1 hour; BV2 microglia cells) inhibits the phosphorylation of IκBα, p65, but enhances the expression of Nrf2 and HO-1[1].
Cannabisin F (0~15 μM; 24 hours; BV2 microglia cells) has no significant effect on cell survival, inhibits IL-6 and TNF-α production and their mRNA expression, inhibits the production of ROS and increases the expression of SIRT1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:BV2 microglia cells
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Concentration:0~15 µM
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Incubation Time:24 hours
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Result:Had no significant effect on cell survival.
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Cell Line:BV2 microglia cells
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Concentration:0~15 µM
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Incubation Time:1 hour
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Result:Inhibited the phosphorylation of IκBα, p65, but enhanced the expression of Nrf2 and HO-1.
Chemical Information
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CAS No. 163136-19-4
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Appearance Solid
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Molecular Weight 624.68
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Formula C36H36N2O8
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Color White to off-white
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SMILES
COC1=C(O)C=CC(/C=C(C(NCCC2=CC=C(O)C=C2)=O)\OC3=C(C=C(/C=C/C(NCCC4=CC=C(O)C=C4)=O)C=C3)OC)=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cannabisin F Related Classifications
HY-N3532 Related Classifications
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