1000306-34-2
Chemical Structure
KVI-020
Synonym(s): WYE-160020
- CAS No.: 1000306-34-2
- Formula:C20H25N3O5S
- Molecular Weight:419.49
IUPAC Name: (R)-N-(3-(4-methoxyphenethyl)-4-(4-methoxyphenyl)-2-oxoimidazolidin-1-yl)methanesulfonamide
InChIKey: GFFIHDXPUGXVGG-IBGZPJMESA-N
SMILES: O=C1N([C@@](C(C=C2)=CC=C2OC)([H])CN1N[S](C)(=O)=O)CCC(C=C3)=CC=C3OC
Biological Activity: KVI-020 is an orally active, potent and selective blocker of the atrial potassium channel Kv1.5, with an IC50 of 480 nM. KVI-020 can inhibits hERG, with an IC50 of 15100 nM. KVI-020 is a potent antiarrhythmic agent, and can be used for atrial fibrillation (AF) research[1].
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KVI-020 | KVI-020 is an orally active, potent and selective blocker of the atrial potassium channel Kv1.5, with an IC50 of 480 nM. KVI-020 can inhibits hERG, with an IC50 of 15100 nM. KVI-020 is a potent antiarrhythmic agent, and can be used for atrial fibrillation (AF) research. | |||||||||||||||||||||
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Keywords
