1010100-22-7
1010100-22-7
Chemical Structure
Thalidomide-5-CH2-NH2 hydrochloride
- CAS No.: 1010100-22-7
- Formula:C14H14ClN3O4
- Molecular Weight:323.73
IUPAC Name: 5-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
InChIKey: ODZXEQVQLJKSQH-UHFFFAOYSA-N
SMILES: NCC1=CC(C(N(C2C(NC(CC2)=O)=O)C3=O)=O)=C3C=C1.Cl
Biological Activity: Thalidomide-5-CH2-NH2 (hydrochloride) is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-CH2-NH2 (hydrochloride) can be connected to the ligand for protein by a linker to form PROTACs[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Thalidomide-5-CH2-NH2 hydrochloride | 98.0% | Thalidomide-5-CH2-NH2 (hydrochloride) is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-CH2-NH2 (hydrochloride) can be connected to the ligand for protein by a linker to form PROTACs. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.91
HY-W4546785-Bromomethylthalidomide -
Similarity Score 0.90
HY-W586327Thalidomide-5-methanol -
Similarity Score 0.89
HY-139545Thalidomide-4-C3-NH2 hydrochloride -
Similarity Score 0.87
HY-139548Thalidomide-5-methyl -
Similarity Score 0.87
HY-W451211Thalidomide-5-carbaldehyde -
Similarity Score 0.86
HY-139546Thalidomide-5-propargyne-NH2 hydrochloride -
Similarity Score 0.85
HY-W4579602-(2,6-Dioxopiperidin-3-yl)-5-ethynylisoindoline-1,3-dione -
Similarity Score 0.85
HY-139539Thalidomide-5-COOH -
Similarity Score 0.85
HY-W0235735-Aminothalidomide -
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