1010731-97-1

CCR1 antagonist 10 Chemical Structure
1010731-97-1

Chemical Structure

CCR1 antagonist 10

  • CAS No.: 1010731-97-1
  • Formula:C30H31ClN2O4
  • Molecular Weight:519.03

IUPAC Name: (S,E)-5-(3-(4-(4-chlorophenyl)-4-hydroxy-3,3-dimethylpiperidin-1-yl)propylidene)-5,11-dihydrobenzo[6,7]oxepino[3,4-b]pyridine-7-carboxylic acid

InChIKey: NVBMQDQKIKYLDW-WXTRKPKDSA-N

SMILES: O=C(C1=CC=C(OCC2=NC=CC=C2/C3=C\CCN4CC(C)(C)[C@@](O)(C5=CC=C(Cl)C=C5)CC4)C3=C1)O

Biological Activity: CCR1 antagonist 10 (example 1) is a potent and orally active CCR1 antagonist. CCR1 antagonist 10 inhibits 125I-MIP-1α binding to THP-1 cell membranes with an Ki value of 2.3 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-15544 		CCR1 antagonist 10 CCR1 antagonist 10 (example 1) is a potent and orally active CCR1 antagonist. CCR1 antagonist 10 inhibits 125I-MIP-1α binding to THP-1 cell membranes with an Ki value of 2.3 nM.
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