103560-62-9
103560-62-9
Chemical Structure
(E)-4-Oxo-2-nonenal
Synonym(s): 4-ONE
- CAS No.: 103560-62-9
- Formula:C9H14O2
- Molecular Weight:154.21
IUPAC Name: (E)-4-oxonon-2-enal
InChIKey: SEPPVOUBHWNCAW-FNORWQNLSA-N
SMILES: O=C/C=C/C(CCCCC)=O
Biological Activity: (E)-4-Oxo-2-nonenal (4-ONE) is one of the major hemolytic decomposition products of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a major product of the FeII-mediated breakdown of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a potent transient receptor potential ankyrin 1 (TRPA1) agonist[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(E)-4-Oxo-2-nonenal | 95.0% | (E)-4-Oxo-2-nonenal (4-ONE) is one of the major hemolytic decomposition products of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a major product of the FeII-mediated breakdown of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a potent transient receptor potential ankyrin 1 (TRPA1) agonist. | ||||||||||||||||||||
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(E)-4-Oxo-2-nonenal-d3 | (E)-4-Oxo-2-nonenal-d3 is the deuterium labeled (E)-4-Oxo-2-nonenal. | |||||||||||||||||||||
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References
- [1]. S H Lee, et al. Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidation. Chem Res Toxicol. 2000 Aug;13(8):698-702. [Content Brief]
- [2]. Fumie Saito, et al. Reaction products of gamma-tocopherol with (E)-4-oxo-2-nonenal in acidic acetonitrile. Biosci Biotechnol Biochem. 2010;74(1):168-74. [Content Brief]
- [3]. Rabea Graepel, et al. 4-oxo-2-nonenal (4-ONE): evidence of transient receptor potential ankyrin 1-dependent and -independent nociceptive and vasoactive responses in vivo. J Pharmacol Exp Ther. 2011 Apr;337(1):117-24. [Content Brief]
