1047634-65-0
1047634-65-0
Chemical Structure
Uprosertib
Synonym(s): GSK2141795
- CAS No.: 1047634-65-0
- Formula:C18H16Cl2F2N4O2
- Molecular Weight:429.25
IUPAC Name: (S)-N-(1-amino-3-(3,4-difluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)furan-2-carboxamide
InChIKey: AXTAPYRUEKNRBA-JTQLQIEISA-N
SMILES: O=C(C1=CC(C2=C(Cl)C=NN2C)=C(Cl)O1)N[C@@H](CC3=CC=C(F)C(F)=C3)CN
Biological Activity: Uprosertib (GSK2141795) is a potent and selective pan-Akt inhibitor with IC50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Uprosertib | 99.93% | Uprosertib (GSK2141795) is a potent and selective pan-Akt inhibitor with IC50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively. | ||||||||||||||||||||
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