10534-89-1
Chemical Structure
Hexaamminecobalt(III) chloride
Synonym(s): Cobalt hexammine trichloride; Hexaamminecobalt trichloride
- CAS No.: 10534-89-1
- Formula:Cl3CoH18N6
- Molecular Weight:267.48
IUPAC Name: 2l2-trichlorane, hexaammonia cobalt salt
InChIKey: BMTNSVZPLARCCA-UHFFFAOYSA-N
SMILES: ClClCl.[Co].N.N.N.N.N.N
Biological Activity: Hexaamminecobalt (III) chloride is an orally active cobalt coordination compound. Hexaamminecobalt (III) chloride restores the activities of liver antioxidant enzymes (SOD, Catalase) and detoxification enzyme GST. Hexaamminecobalt (III) chloride restores GSH content and reduces DAG. Hexaamminecobalt (III) chloride impairs renal function. Hexaamminecobalt (III) chloride exerts anti-carcinogenic effects in Diethylnitrosamine (HY-N7434)-induced hepatocarcinoma[1][2][3].
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Hexaamminecobalt(III) chloride | 99.50% | Hexaamminecobalt (III) chloride is an orally active cobalt coordination compound. Hexaamminecobalt (III) chloride restores the activities of liver antioxidant enzymes (SOD, Catalase) and detoxification enzyme GST. Hexaamminecobalt (III) chloride restores GSH content and reduces DAG. Hexaamminecobalt (III) chloride impairs renal function. Hexaamminecobalt (III) chloride exerts anti-carcinogenic effects in Diethylnitrosamine (HY-N7434)-induced hepatocarcinoma. | ||||||||||||||||||||
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- [1]. Naura AS, et al. Toxic effects of hexaammine cobalt(III) chloride on liver and kidney in mice: Implication of oxidative stress. Drug Chem Toxicol. 2009;32(3):293-9. [Content Brief]
- [2]. Naura AS, et al. Anticarcinogenic effects of hexaamminecobalt(III) chloride in mice initiated with diethylnitrosamine. Biol Trace Elem Res. 2007 Nov;119(2):147-65. [Content Brief]
- [3]. Naura AS, et al. Studies on mode of action of hexaammine Co(III) chloride against diethylnitrosamine-induced hepatocarcinogenesis in mice. J Biochem Mol Toxicol. 2009 May-Jun;23(3):193-201. [Content Brief]
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