106243-16-7
106243-16-7
Chemical Structure
Thioperamide
Synonym(s): MR-12842
- CAS No.: 106243-16-7
- Formula:C15H24N4S
- Molecular Weight:292.44
IUPAC Name: N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide
InChIKey: QKDDJDBFONZGBW-UHFFFAOYSA-N
SMILES: S=C(N1CCC(C2=CN=CN2)CC1)NC3CCCCC3
Biological Activity: Thioperamide (MR-12842) is a potent, orally available, brain penetrant and selective H3 receptor antagonist with a Ki of 4.3 nM for inhibition of [3H]histamine release. Thioperamide inhibits [3H]histamine synthesis with a Ki of 31 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Thioperamide | 99.91% | Thioperamide (MR-12842) is a potent, orally available, brain penetrant and selective H3 receptor antagonist with a Ki of 4.3 nM for inhibition of [3H]histamine release. Thioperamide inhibits [3H]histamine synthesis with a Ki of 31 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.67
HY-107559GT-2016 -
Similarity Score 0.58
HY-B1813A(±)-Vesamicol hydrochloride -
Similarity Score 0.58
HY-167897UR-AK49 -
Similarity Score 0.58
HY-113995(-)-Vesamicol -
Similarity Score 0.58
HY-113995Arel-(-)-Vesamicol -
Similarity Score 0.58
HY-121470Vesamicol -
Similarity Score 0.58
HY-W795736(+)-Vesamicol -
Similarity Score 0.57
HY-W013989R1,3-Dicyclohexylurea (Standard) -
Similarity Score 0.57
HY-129415Esaprazole -
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