1109276-89-2
1109276-89-2
Chemical Structure
PF-04620110
- CAS No.: 1109276-89-2
- Formula:C21H24N4O4
- Molecular Weight:396.44
IUPAC Name: 2-((1r,4r)-4-(4-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl)cyclohexyl)acetic acid
InChIKey: GEVVQZHMFVFGLN-HDJSIYSDSA-N
SMILES: O=C(C[C@@H]1CC[C@H](CC1)C2=CC=C(C=C2)N3CCOC4=NC=NC(N)=C4C3=O)O
Biological Activity: PF-04620110 is a potent, selective and orally bioavailable diglyceride acyltransferase-1 (DGAT-1) inhibitor with an IC50 of 19 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-04620110 | 99.60% | PF-04620110 is a potent, selective and orally bioavailable diglyceride acyltransferase-1 (DGAT-1) inhibitor with an IC50 of 19 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.60
HY-32219T863 -
Similarity Score 0.59
HY-112851Diacylglycerol acyltransferase inhibitor-1 -
Similarity Score 0.46
HY-W998257Thalidomide-piperidine-C-COOH -
Similarity Score 0.45
HY-W998260Pomalidomide-cyclohexane-C-COOH -
Similarity Score 0.44
HY-118326MRT 68601 -
Similarity Score 0.44
HY-139171F092 -
Similarity Score 0.44
HY-783972-((1s,4s)-4-Phenylcyclohexyl)acetic acid -
Similarity Score 0.44
HY-110341MRT 68601 hydrochloride -
Similarity Score 0.43
HY-W998294E3 ligase Ligand PG-piperidine-C2-OH -
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