1113044-49-7
Chemical Structure
FIT-039
- CAS. Nr.: 1113044-49-7
- Formula:C17H18FN3S
- Molecular Weight:315.41
IUPAC Name: N-(5-fluoro-2-(piperidin-1-yl)phenyl)pyridine-4-carbothioamide
InChIKey: VRKZHYSJZOUICG-UHFFFAOYSA-N
SMILES: FC1=CC(NC(C2=CC=NC=C2)=S)=C(N3CCCCC3)C=C1
Biological Activity: FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
FIT-039 | 99.56% | FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
FIT-039 (Standard) | ≥98% | FIT-039 (Standard) is the analytical standard of FIT-039. This product is intended for research and analytical applications. FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.68
HY-13949SRPIN340 -
Similarity Score 0.60
HY-165245SBI-183 -
Similarity Score 0.59
HY-18063AML252 hydrochloride -
Similarity Score 0.59
HY-18063ML252 -
Similarity Score 0.59
HY-19172349U85 hydrochloride -
Similarity Score 0.58
HY-149597Lysyl hydroxylase 2-IN-1 -
Similarity Score 0.58
HY-W112331N-(3-Fluoropyridin-4-yl)isonicotinamide -
Similarity Score 0.57
HY-W4564081,4-Di(pyridin-4-yl)piperazine -
Similarity Score 0.57
HY-19618BRD3308 -
Explore the MedChemAI to find more analogs
