1113044-49-7
Chemical Structure
FIT-039
- CAS No.: 1113044-49-7
- Formula:C17H18FN3S
- Molecular Weight:315.41
IUPAC Name: N-(5-fluoro-2-(piperidin-1-yl)phenyl)pyridine-4-carbothioamide
InChIKey: VRKZHYSJZOUICG-UHFFFAOYSA-N
SMILES: FC1=CC(NC(C2=CC=NC=C2)=S)=C(N3CCCCC3)C=C1
Biological Activity: FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.
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FIT-039 | 99.56% | FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses. | ||||||||||||||||||||
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FIT-039 (Standard) | ≥98% | FIT-039 (Standard) is the analytical standard of FIT-039. This product is intended for research and analytical applications. FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses. | ||||||||||||||||||||
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Keywords
