1116571-01-7
1116571-01-7
Chemical Structure
LIMK-IN-1
- CAS 番号: 1116571-01-7
- Formula:C20H21BrN8
- Molecular Weight:453.34
IUPAC Name: (S,Z)-N-(3-bromophenyl)-N'-cyano-2-methyl-4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperazine-1-carboximidamide
InChIKey: KSECQYDNQYAZMQ-AWEZNQCLSA-N
SMILES: CC1=CNC2=NC=NC(N3C[C@H](C)N(/C(NC4=CC=CC(Br)=C4)=N\C#N)CC3)=C21
Biological Activity: LIMK-IN-1 (Compound 14) is an inhibitor of LIM-Kinase (LIMK), with IC50s of 0.5 nM and 0.9 nM for LIMK1 and LIMK2, respectively. LIMK-IN-1 can be used for ocular hypertension and associated glaucoma research[1].
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LIMK-IN-1 | 99.33% | LIMK-IN-1 (Compound 14) is an inhibitor of LIM-Kinase (LIMK), with IC50s of 0.5 nM and 0.9 nM for LIMK1 and LIMK2, respectively. LIMK-IN-1 can be used for ocular hypertension and associated glaucoma research. | ||||||||||||||||||||
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