112448-39-2
112448-39-2
Chemical Structure
3'-Demethylnobiletin
- CAS No.: 112448-39-2
- Formula:C20H20O8
- Molecular Weight:388.37
IUPAC Name: 2-(3-hydroxy-4-methoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one
InChIKey: XFYYZBJXMSDKCV-UHFFFAOYSA-N
SMILES: O=C1C=C(C2=CC=C(OC)C(O)=C2)OC3=C(OC)C(OC)=C(OC)C(OC)=C13
Biological Activity: 3'-Demethylnobiletin, a derivative of Nobiletin, is a polymethoxyflavonoid in citrus fruits[1]. Nobiletin exhibits anticancer activity and inhibits tumor angiogenesis by regulating Src, FAK, and STAT3 signaling[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3'-Demethylnobiletin | 99.98% | 3'-Demethylnobiletin, a derivative of Nobiletin, is a polymethoxyflavonoid in citrus fruits. Nobiletin exhibits anticancer activity and inhibits tumor angiogenesis by regulating Src, FAK, and STAT3 signaling. | ||||||||||||||||||||
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References
- [1]. Murakami A, et al. In vitro absorption and metabolism of nobiletin, a chemopreventive polymethoxyflavonoid in citrus fruits. Biosci Biotechnol Biochem. 2001 Jan;65(1):194-7. [Content Brief]
- [2]. Sp N, et al. Nobiletin Inhibits Angiogenesis by Regulating Src/FAK/STAT3-Mediated Signaling through PXN in ER+ Breast Cancer Cells. Int J Mol Sci. 2017 Apr 30;18(5). pii: E935. [Content Brief]
