112448-39-2
112448-39-2
Chemical Structure
3'-Demethylnobiletin
- CAS No.: 112448-39-2
- Formula:C20H20O8
- Molecular Weight:388.37
IUPAC Name: 2-(3-hydroxy-4-methoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one
InChIKey: XFYYZBJXMSDKCV-UHFFFAOYSA-N
SMILES: O=C1C=C(C2=CC=C(OC)C(O)=C2)OC3=C(OC)C(OC)=C(OC)C(OC)=C13
Biological Activity: 3'-Demethylnobiletin, a derivative of Nobiletin, is a polymethoxyflavonoid in citrus fruits[1]. Nobiletin exhibits anticancer activity and inhibits tumor angiogenesis by regulating Src, FAK, and STAT3 signaling[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
3'-Demethylnobiletin | 99.98% | 3'-Demethylnobiletin, a derivative of Nobiletin, is a polymethoxyflavonoid in citrus fruits. Nobiletin exhibits anticancer activity and inhibits tumor angiogenesis by regulating Src, FAK, and STAT3 signaling. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.92
HY-1420664′-Demethylnobiletin -
Similarity Score 0.89
HY-N0155Nobiletin -
Similarity Score 0.87
HY-N10078Gardenin D -
Similarity Score 0.86
HY-N197807-Hydroxy-5,6,8,3',4'-pentamethoxyflavone -
Similarity Score 0.85
HY-N1942R5-O-Demethylnobiletin (Standard) -
Similarity Score 0.84
HY-N0133RTangeretin (Standard) -
Similarity Score 0.81
HY-N118148-Methoxycirsilineol -
Similarity Score 0.81
HY-N11106Gardenin C -
Similarity Score 0.80
HY-1346025'-Methoxynobiletin -
Explore the MedChemAI to find more analogs
References
- [1]. Murakami A, et al. In vitro absorption and metabolism of nobiletin, a chemopreventive polymethoxyflavonoid in citrus fruits. Biosci Biotechnol Biochem. 2001 Jan;65(1):194-7. [Content Brief]
- [2]. Sp N, et al. Nobiletin Inhibits Angiogenesis by Regulating Src/FAK/STAT3-Mediated Signaling through PXN in ER+ Breast Cancer Cells. Int J Mol Sci. 2017 Apr 30;18(5). pii: E935. [Content Brief]
