1137359-47-7
Chemical Structure
BRD7552
- CAS No.: 1137359-47-7
- Formula:C33H33N3O15
- Molecular Weight:711.63
IUPAC Name: ethyl 4-(((((2R,3R,4S,5R,6S)-4,5-bis((benzo[d][1,3]dioxol-5-ylcarbamoyl)oxy)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3-yl)oxy)carbonyl)amino)benzoate
InChIKey: AAOLIMLEFKWKOY-IXMSMLDRSA-N
SMILES: OC[C@@H](O1)[C@@H](OC(NC2=CC=C(C(OCC)=O)C=C2)=O)[C@H](OC(NC3=CC=C(OCO4)C4=C3)=O)[C@@H](OC(NC5=CC=C(OCO6)C6=C5)=O)[C@H]1OC
Biological Activity: BRD7552, a potent PDX1 transcription factor inducer, upregulates PDX1 expression in both primary human islets and ductal cells, and induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. BRD7552 increases insulin expression. PDX1 is a key transcription factor involved in pancreas development and β cell function[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BRD7552 | 99.81% | BRD7552, a potent PDX1 transcription factor inducer, upregulates PDX1 expression in both primary human islets and ductal cells, and induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. BRD7552 increases insulin expression. PDX1 is a key transcription factor involved in pancreas development and β cell function. | ||||||||||||||||||||
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Keywords
