116064-77-8
116064-77-8
Chemical Structure
Dehydromiltirone
Synonym(s): 1,2-Didehydromiltirone
- CAS No.: 116064-77-8
- Formula:C19H20O2
- Molecular Weight:280.36
IUPAC Name: 2-isopropyl-8,8-dimethyl-7,8-dihydrophenanthrene-3,4-dione
InChIKey: FQRLDPKLRMEKLQ-UHFFFAOYSA-N
SMILES: O=C1C(C(C)C)=CC2=C(C3=C(C=C2)C(C)(C)CC=C3)C1=O
Biological Activity: Dehydromiltirone (1,2-Didehydromiltirone) is a diterpenoid quinone with an anti-inflammatory effect. Dehydromiltirone prevents liver injury by modifying the MAPK and NF-κB signaling pathways, reducing neuroinflammatory responses, and inhibiting platelet aggregation. Dehydromiltirone can be used for osteoporosis research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dehydromiltirone | 99.11% | Dehydromiltirone (1,2-Didehydromiltirone) is a diterpenoid quinone with an anti-inflammatory effect. Dehydromiltirone prevents liver injury by modifying the MAPK and NF-κB signaling pathways, reducing neuroinflammatory responses, and inhibiting platelet aggregation. Dehydromiltirone can be used for osteoporosis research. | ||||||||||||||||||||
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References
- [1]. Shuqiang Yue, et al. Salvia miltiorrhiza compounds protect the liver from acute injury by regulation of p38 and NFκB signaling in Kupffer cells. Pharm Biol. 2014 Oct;52(10):1278-85. [Content Brief]
- [2]. Wei Deng, et al. Dehydromiltirone inhibits osteoclast differentiation in RAW264.7 and bone marrow macrophages by modulating MAPK and NF-κB activity. Front Pharmacol. 2022 Sep 21;13:1015693. [Content Brief]
