1185003-07-9
1185003-07-9
Chemical Structure
Fludioxonil-13C3
Synonym(s): CGA-173506-13C3
- CAS No.: 1185003-07-9
- Formula:C913C3H6F2N2O2
- Molecular Weight:251.16
InChIKey: MUJOIMFVNIBMKC-XWKFXZGISA-N
SMILES: FC1(OC2=C([13C]3=CNC=[13C]3[13C]#N)C=CC=C2O1)F
Biological Activity: Fludioxonil-13C3 (CGA-173506-13C3) is 13C labeled Fludioxonil. Fludioxonil (CGA-173506) is a phenylpyrrole-type fungicide with oral activity that can inhibit the growth of S. sclerotiorum. Fludioxonil promotes tumor growth and metastasis, and induces cardiac toxicity. Fludioxonil causes cytoskeletal disruption, DNA damage, and apoptosis in mouse glioma cells[1][2][3][4].
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Fludioxonil-13C3 | Fludioxonil-13C3 (CGA-173506-13C3) is 13C labeled Fludioxonil. Fludioxonil (CGA-173506) is a phenylpyrrole-type fungicide with oral activity that can inhibit the growth of S. sclerotiorum. Fludioxonil promotes tumor growth and metastasis, and induces cardiac toxicity. Fludioxonil causes cytoskeletal disruption, DNA damage, and apoptosis in mouse glioma cells. | |||||||||||||||||||||
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Fludioxonil (Standard) | ≥98% | Fludioxonil (Standard) is the analytical standard of Fludioxonil. This product is intended for research and analytical applications. Fludioxonil, a phenylpyrrole fungicide, has a strong inhibition on mycelia growth of S. sclerotiorum. | ||||||||||||||||||||
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Fludioxonil | 99.94% | Fludioxonil (CGA-173506) is a phenylpyrrole-type fungicide with oral activity that can inhibit the growth of S. sclerotiorum. Fludioxonil promotes tumor growth and metastasis, and induces cardiac toxicity. Fludioxonil causes cytoskeletal disruption, DNA damage, and apoptosis in mouse glioma cells. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Yabing Duan, et al. effect of phenylpyrrole fungicide fludioxonil on morphological and physiological characteristics of Sclerotinia sclerotiorum. Pesticide Biochemistry and Physiology Volume 106, Issues 1-2, May-June 2013, Pages 61-67.
- [3]. Ryeo-Eun Go, et al. Fludioxonil induced the cancer growth and metastasis via altering epithelial-mesenchymal transition via an estrogen receptor-dependent pathway in cellular and xenografted breast cancer models. Environ Toxicol. 2017 Apr;32(4):1439-1454. [Content Brief]
- [4]. Imen Graiet, et al. Fludioxonil, a phenylpyrrol pesticide, induces Cytoskeleton disruption, DNA damage and apoptosis via oxidative stress on rat glioma cells. Food Chem Toxicol. 2022 Dec:170:113464. [Content Brief]
