118675-83-5
118675-83-5
Chemical Structure
DDPO
- CAS No.: 118675-83-5
- Formula:C21H24N6O4
- Molecular Weight:424.45
IUPAC Name: (S)-5-amino-2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl)amino)benzamido)pentanoic acid
InChIKey: XXHSFOMKJAVUID-KRWDZBQOSA-N
SMILES: O=C1C2=CC(CNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCCN)=O)=CC=C2NC(N)=N1
Biological Activity: DDPO is an inhibitor for dihydrofolate reductase (DHFR) with an IC50 of 0.035 µM. DDPO inhibits the cell growth of cancer cell L1210 and WI-L2with IC50 of 5 and 0.28 µM[1].
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DDPO | DDPO is an inhibitor for dihydrofolate reductase (DHFR) with an IC50 of 0.035 µM. DDPO inhibits the cell growth of cancer cell L1210 and WI-L2with IC50 of 5 and 0.28 µM. | |||||||||||||||||||||
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References
Keywords
